Table 1 Concordance of TP53 expression by IHC with TP53 mutation status in mucinous borderline tumors and mucinous carcinomas from the Genomic Analysis of Mucinous Tumors (GAMuT) cohort.

From: Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

 

TP53 mutation type

 

TP53 IHC

Missense

Inframe indel

Truncating

Splicing

NMD

Total

Abnormal OE

54

3

0

2

3

62

Abnormal CA

0

0

12

2

1

15

Abnormal CY

0

0

0

0

0

0

Normal

2

0

1

0

33

36

Total

56

3

13

4

37

113

  1. OE overexpression, CA complete absence, CY cytoplasmic, NMD no mutation detected.