Fig. 1: Gross and microscopic features.
From: Superficial ALK-rearranged myxoid spindle cell neoplasm with a novel FMR1-ALK fusion gene
A A lobulated subcutaneous tumor with rich vascularization on the outer surface. B, C Microscopically, the tumor shows a predominantly reticular (B) to cord-like (C) pattern in a hyalinized stroma, accompanied by thin-walled ectatic vessels. D The tumor cells have round to ovoid nuclei, fine chromatin, scant cytoplasm, and occasional intranuclear pseudoinclusions (arrows). E Some vessels show perivascular hyalinization or edematous change. F Focally, the tumor shows spindle cells arranged in whorl-like structures.
