Table 2 Malignant lesions on core needle biopsy.

From: Breast lesions associated with mammographic architectural distortion: a study of 588 core needle biopsies

Feature

Number (%)

Invasive carcinoma

164

Histologic type

    Microinvasive (not typed)

3 (2%)

      No special type (“ductal”)

63 (38%)

    Mixed ductal and lobular

31 (19%)

    Lobular

53 (32%)

    Tubulolobular

2 (1%)

    Tubular

12 (7%)

Grade

    Microinvasive (not graded)

3 (2%)

    1

98 (60%)

    2

59 (36%)

    3

4 (2%)

Estrogen receptor

    Positive

160 (98%)

    Negative

4 (2%)

Progesterone receptor

    Positive

134 (82%)

    Negative

29 (18%)

HER2

    Positive

3 (2%)

    Negative

161 (98%)

Biologic type

    Luminal-like (ER+/HER2−)

158 (96%)

    Luminal/HER2-like (ER+/HER2+)

2 (1%)

    HER2-like (ER−/PR-/HER2+)

1 (1%)

    Basal-like (ER−/PR−/HER2−)

3 (2%)

T classification (after excision) (n = 129):a

No special type (“ductal”) (n = 54)

Lobular or mixed ductal and lobular (n = 75)

    T1a (>0.1–0.5 cm)

9 (17%)

4 (5%)

    T1b (>0.5–1.0 cm)

15 (28%)

16 (21%)

    T1c (>1.0–2.0 cm)

26 (48%)

34 (45%)

    T2 (>2.0–5.0 cm)

3 (6%)

20 (27%)

    T3 (>5.0 cm)

1 (2%)

1 (1%)

Lymph nodes (n = 119)b

    N0

97 (82%)

    N1

15 (13%)

    N2

4 (3%)

    N3

3 (3%)

AJCC Pathologic Prognostic Stage Group (n = 114)c

    I

105 (92%) (91 IA, 14 IB)

    II

2 (2%)

    III

5 (4%)

    IV

2 (2%)

Ductal carcinoma in situ

20

Nuclear grade

    1

1 (5%)

    2

11 (55%)

    3

8 (40%)

Necrosis

    Present

12 (60%)

    Absent

8 (40%)

Calcifications

    Present

16 (80%)

    Absent

4 (20%)

Estrogen receptor

    Positive

18 (90%)

    Negative

2 (10%)

Extent

    Average no. of blocks

12

    Range

4–38

Associated lesion

    Sclerosing

13 (65%)

    Papilloma

1 (5%)

    None

6 (30%)

  1. aMicroinvasive carcinoma, tubular carcinoma, tubulolobular carcinoma, and carcinomas after treatment are not included. Ten cancers had insufficient information for T classification.
  2. bLymph node status is not available for 45 patients because either the nodes were not sampled or the results were not available.
  3. cAJCC Pathologic Prognostic Stage could not be assigned to 50 women with invasive carcinoma because nodes were not evaluated, the patient received neoadjuvant therapy, or follow-up was not available.