Fig. 4: Overlap of impulsivity, neuroticism, and alcohol-use risk networks.

a The shared vs. unique connections that predict impulsivity, neuroticism and alcohol-use risk, as represented in a Venn diagram. Impulsivity and neuroticism overlap with the alcohol-use risk network via distinct functional connections. b The shared connections summarized by connectivity between large-scale canonical networks. c The overlap of shared connections, as separated by positive and negative networks. The edges in the impulsivity (blue) and neuroticism (yellow) networks that distinctively overlap with the alcohol-use risk network mostly predict the trait and alcohol-use in the same direction. Very few edges are found to consistently predict impulsivity, neuroticism, and alcohol-use in the same direction (purple), suggesting unique contributions of each trait to alcohol-use risk.