Table 2 Severity of mental health problems, impairment and functioning and experiences of the milestone cohort assessed at baseline by medication grouP (T1, N = 690).

From: Mental health trajectories of adolescents treated with psychotropic medications: insights from the european milestone study

 

Mean (SD) or N (%)

 

Group 1* (N = 186)

Group 2* (N = 304)

Group 3* (N = 200)

p-value**

SEVERITY OF MENTAL HEALTH PROBLEMS

Clinician rated severity of psychopathology (CGI-S)

 

Not at all ill

15 (8.1%)

18 (5.9%)

29 (14.5%)

0.018

Borderline/mildly/moderately ill

108 (58.1%)

179 (58.9%)

125 (62.5%)

Markedly ill or more severe

38 (20.4%)

65 (21.4%)

31 (15.5%)

Missing

25 (13.4%)

42 (13.8%)

15 (7.5%)

Mental health (HoNOSCA; range 0–52)

13.9 (9.6)

12.8 (8.6)

9.3 (7.0)

<0.001

Lifetime suicide attempt

Yes

56 (30.1%)

90 (29.6%)

34 (17.0%)

<0.001

No

116 (62.4%)

193 (63.5%)

161 (80.5%)

Missing

14 (7.5%)

21 (6.9%)

5 (2.5%)

Non-accidental self-injury (HoNOSCA domain)

No problem of this kind

125 (67.2%)

203 (66.8%)

163 (81.5%)

<0.001

Occasional thoughts about death, or of self-harm not leading to injury. No self-harm or suicidal thoughts.

21 (11.3%)

25 (8.2%)

15 (7.5%)

Non-hazardous self-harm whether or not associated with suicidal thoughts

9 (4.8%)

20 (6.6%)

12 (6.0%)

Moderately severe suicidal intent or moderate non-hazardous self-harm

16 (8.6%)

28 (9.2%)

7 (3.5%)

Serious suicidal attempt or serious deliberate self-injury

12 (6.5%)

17 (5.6%)

3 (1.5%)

Missing

3 (1.6%)

11 (3.6%)

0 (0.0%)

Quality of life (WHOQOL-BREF; range 4–20)

Psychological

17.2 (3.9)

17.3 (3.7)

18.6 (3.3)

<0.001

Physical

20.8 (3.7)

20.7 (3.8)

20.9 (3.0)

0.048

Social

10.4 (2.5)

10.1 (2.3)

10.6 (2.4)

0.007

Environmental

30.8 (5.1)

29.7 (5.4)

30.1 (4.7)

<0.001

Total

79.2 (12.1)

77.9 (12.1)

80.2 (10.5)

<0.001

Everyday functional skills (SLOF)

Physical functioning

24.1 (1.6)

24.2 (1.6)

24.1 (1.5)

0.023

Personal care skills

33.1 (2.6)

33.5 (2.4)

33.7 (2.7)

<0.001

Interpersonal relationships

24.6 (6.8)

25.8 (6.2)

27.5 (6.6)

<0.001

Social acceptability

30.7 (3.9)

31.1 (3.6)

32.3 (3.1)

<0.001

Activities

48.3 (7.8)

49.9 (5.7)

50.7 (5.7)

<0.001

Work skills

22.8 (6.3)

23.9 (5.3)

24.1 (6.0)

<0.001

Total

183.5 (21.7)

188.8 (17.7)

192.5 (17.5)

<0.001

Life events (range 0–13)

1.7 (1.7)

2.1 (1.7)

1.8 (1.6)

<0.001

Bullying

Victim

72 (38.7%)

110 (36.2%)

88 (44.0%)

<0.001

Bully/victim

70 (37.6%)

119 (39.1%)

66 (33.0%)

Bully

4 (2.2%)

13 (4.3%)

5 (2.5%)

Non-involved

37 (19.9%)

52 (17.1%)

37 (18.5%)

Missing

3 (1.6%)

10 (3.3%)

4 (2.0%)

  1. * Group 1 = Continuous Medication, Group 2 = Intermittent Medication, Group 3 = Never Medicated.
  2. ** P-values in bold are statistically significant.