Table 1 List of upregulated proteins in hippocampus of eEF2K-cKI mice.

From: Overactive Neuronal eEF2K/eEF2 signaling is associated with cognitive impairment and apathy-like behavior

Accession

Protein Name

p-value

FDR

Fold Change

P58252

Elongation factor 2

4.64E-11

8.42E-08

0.905

D3YZU1

SH3 and multiple ankyrin repeat domains protein 1

2.4E-06

0.000546

0.483

Q9WUA2

Phenylalanine--tRNA ligase beta subunit

0.002301

0.037622

0.446

Q9D273

Corrinoid adenosyltransferase

0.000829

0.020343

0.432

P20357

Microtubule-associated protein 2

1.08E-07

9.84E-05

0.421

P14148

60S ribosomal protein L7

1.76E-06

0.000531

0.403

Q9CQH7

Transcription factor BTF3 homolog 4

0.000109

0.005517

0.396

P47911

60S ribosomal protein L6

0.000141

0.006551

0.386

Q922Q8

Leucine-rich repeat-containing protein 59

0.000199

0.008053

0.380

P03995

Glial fibrillary acidic protein

0.000361

0.011917

0.365

Q9CQR2

40S ribosomal protein S21

9.8E-05

0.005232

0.365

Q9CWM4

Prefoldin subunit 1

0.001577

0.029499

0.362

Q9QUR7

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

0.001344

0.027729

0.358

P53026

60S ribosomal protein L10a

2.13E-06

0.000546

0.357

O35114

Lysosome membrane protein 2

0.003125

0.044664

0.356

Q9CZX8

40S ribosomal protein S19

3.65E-06

0.000737

0.355

P62900

60S ribosomal protein L31

0.0018

0.031959

0.352

P98086

Complement C1q subcomponent subunit A

0.000702

0.017448

0.349

P68040

Receptor of activated protein C kinase 1

1.74E-05

0.00188

0.346

Q9D898

Actin-related protein 2/3 complex subunit 5-like protein

0.000948

0.021779

0.324

Q80X50

Ubiquitin-associated protein 2-like

0.000262

0.009706

0.323

P97351

40S ribosomal protein S3a

0.000573

0.015519

0.316

P14206

40S ribosomal protein SA

0.00015

0.006785

0.316

P35980

60S ribosomal protein L18

4.07E-06

0.000739

0.316

Q91ZP9

N-terminal EF-hand calcium-binding protein 2

2E-05

0.002021

0.312

Q9CPR4

60S ribosomal protein L17

0.00059

0.015682

0.312

P25444

40S ribosomal protein S2

0.000967

0.021779

0.304

P63325

40S ribosomal protein S10

0.000431

0.013216

0.304

P63216

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3

0.000972

0.021779

0.303

P99027

60S acidic ribosomal protein P2

6.66E-05

0.003901

0.300

P14115

60S ribosomal protein L27a

4.33E-05

0.003295

0.299

P30416

Peptidyl-prolyl cis-trans isomerase FKBP4

8.89E-05

0.004968

0.299

Q8BGD5

Carnitine O-palmitoyltransferase 1, brain isoform

0.001853

0.032337

0.297

P63323

40S ribosomal protein S12

0.00013

0.006216

0.296

Q921L3

Calcium load-activated calcium channel

0.00016

0.006983

0.296

P62858

40S ribosomal protein S28

0.001559

0.029472

0.294

Q8BTZ7

Mannose-1-phosphate guanyltransferase beta

0.002748

0.041567

0.288

Q6R891

Neurabin-2

7.07E-07

0.000262

0.287

Q8VCM8

Nicalin

1.59E-05

0.00188

0.281

Q9CR57

60S ribosomal protein L14

1.31E-05

0.001695

0.281

O08914

Fatty-acid amide hydrolase 1

0.001496

0.028859

0.276

Q6GQT9

Nodal modulator 1

0.000438

0.013216

0.269

P63028

Translationally-controlled tumor protein

0.001387

0.028277

0.266

Q9D8E6

60S ribosomal protein L4

1.21E-05

0.001684

0.265