Table 3 Five downregulated DEGs only shared between Sh3+/−+LPS vs. WT + LPS and Sh3+/−+LPS vs. Sh3+/−+PBS, not include in WT + LPS vs. WT + PBS.

From: Inflammation increases the penetrance of behavioral impairment in Shank3 haploinsufficiency mice — can it explain the behavioral regression in Autism?

Gene name

Protein function

4930415F15Rik

SPMIP7 (sperm microtubule inner protein 7) is predicted to be involved in spermatogenesis but is also expressed in the brain and its function is unclear.

AC173482.5

Predicted gene, Gm47797

Gm14393

Predicted gene

Gm5111

Predicted gene

Tgif2

TGIF2 (TGF-β-induced factor homeobox 2) is a transcriptional repressor and its downregulation is correlated with neuronal apoptosis and development of autism in mice [95].

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