Fig. 1: Longitudinal human DNA methylation (DNAm) atlas.
From: A longitudinal DNA methylation atlas and its link to brain structure and mental health
Correlation matrix of longitudinal DNAm change (ΔDNAm = DNAm19 - DNAm14) across 175 consensus co-methylation modules identified using WGCNA. Each cell reflects the Pearson correlation between longitudinal change scores of two modules. Hierarchical clustering of this matrix yielded 18 higher-order DNAm clusters (C1–C18), representing coordinated methylation trajectories across adolescence.
