Fig. 3: Outline of the classes and putative mechanisms of VCID treatments with current evidence and those currently in development. | Neuropsychopharmacology

Fig. 3: Outline of the classes and putative mechanisms of VCID treatments with current evidence and those currently in development.

From: Vascular cognitive impairment and dementia: Prevention, treatments, mechanisms and management options for the future

Fig. 3: Outline of the classes and putative mechanisms of VCID treatments with current evidence and those currently in development.

The top half of the diagram outlines treatments with current evidence and the bottom half outlines treatments still under development. The medications and medication classes listed are not exhaustive and are intended to give a sense of the breadth of approaches being taken. AChE Acetylcholinesterase, Ach Acetylcholine, ACEI Angiotensin Converting Enzyme Inhibitor, ARB Angiotensin Receptor Blocker, BB Beta-Blockers, Ca2+ Calcium, CCB Calcium Channel Blockers, DAT dopamine reuptake transport, D receptor Dopamine receptor, GLP-RA1 glucagon-like peptide-1 receptor agonists, ISMN Isosorbide mononitrate, Na+ Sodium, NA RT Noradrenaline reuptake transporter, TMS Transcranial Magnetic Stimulation, tPBM Transcranial photobiomodulation.

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