Fig. 3: Group differences in right centromedial amygdala (rCMA) resting-state functional connectivity (FC). | Neuropsychopharmacology

Fig. 3: Group differences in right centromedial amygdala (rCMA) resting-state functional connectivity (FC).

From: Identification of an intrusive-hypervigilant phenotype of posttraumatic stress symptoms with unique stress peptide and amygdala functional connectivity profiles

Fig. 3: Group differences in right centromedial amygdala (rCMA) resting-state functional connectivity (FC).The alternative text for this image may have been generated using AI.

A Whole-brain contrasts (IH > non-IH) revealed three significant clusters showing greater rCMA FC in the Intrusive-Hypervigilant (IH) group within the parietooccipital sulcus (POS), precuneus (Precun), and medial prefrontal cortex (mPFC). B Radar plot depicting the number of voxels within the significant clusters that overlap with the 7 networks of the Yeo atlas, demonstrating the clusters were predominantly within the default mode network (DMN) and visual network. C Post hoc individual group contrasts revealed that the IH group showed significantly greater rCMA FC than both the High and Low symptom groups across all three clusters. FPN frontoparietal network, SM somatomotor network, VAN ventral attention network, DAN dorsal attention network, **** < 0.001, ***** < 0.0005, ****** < 0.0001.

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