Fig. 4: Connectome patterns and associations with substance use.

A Connectome pattern of predictive networks at age 19. B Connectome pattern of predictive networks at age 23. Pink and blue color represent positive and negative networks separately. C Correlation between cigarette and cannabis use (Cig+CB) and combined network strength derived from Go trials. MF Medial frontal, FP Frontoparietal, DMN Default mode, MOT Motor, VI Visual I, VII Visual II, Vas Visual association, SAL Salience, SC Subcortical, CBL Cerebellar. R/L, right/left hemisphere. *, P < 0.05; **, P < 0.01; ***, P < 0.001.