Table 2 Baseline values

From: Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes

 

Olive oil (a)

C4-Dietary oil (b)

Carrot (c)

P value

GLP-1

10.0 ± 0.9

8.1 ± 0.5

8.7 ± 0.6

0.01a>b

GIP

12.5 ± 2.1

7.3 ± 1.2

8.6 ± 1.0

0.02a>b

PYY

63.1 ± 7.1

52.7 ± 5.5

58.1 ± 7.9

0.51

Glucose

8.9 ± 0.9

8.8 ± 1.0

9.2 ± 1.1

0.28

C-peptide

1,302 ± 79

1,270 ± 99

1,412 ± 86

0.11

Insulin

123 ± 15

113 ± 12

146 ± 16

0.05

Glucagon

12.7 ± 1.5

12.1 ± 1.3

12.6 ± 1.5

0.80

CCK

0.8 ± 0.2

1.0 ± 0.3

0.8 ± 0.2

0.34

Triglycerides

1.3 ± 0.2

1.3 ± 0.2

1.2 ± 0.2

0.86

  1. Data are mean values ± SEM. All values in pM except glucose in mM. P values were calculated using repeated measurement ANOVA. P values ≤ 0.05 are considered statistically significant. Statistical significant differences between the three treatments are shown using the letters a, b and c, referring to the treatments
  2. CCK cholecystokinin, GIP glucose-dependent insulinotropic polypeptide (intact), GLP-1 glucagon-like peptide-1 (total), PYY peptide YY
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