Table 3 Cardiac dimensions and systolic and diastolic cardiac function before and after very low calorie diet

From: Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes

 

Before VLCD

After VLCD

p value

Cardiac dimensions and function

 LV mass (g)

114 ± 27

104 ± 27

<0.001

 LV mass index (g/m2)

53 ± 11

53 ± 12

0.418

 EDV (mL)

175 ± 38

183 ± 40

0.033

 EDVI (mL/m2)

82 ± 15

93 ± 17

<0.001

 ESV (mL)

81 ± 29

82 ± 31

0.481

 ESVI (mL/m2)

38 ± 13

41 ± 15

<0.001

 LV mass/EDV

0.66 ± 0.11

0.57 ± 0.09

<0.001

 SV (mL)

94 ± 18

101 ± 17

0.007

 SVI (mL/m2)

44 ± 7

51 ± 6

<0.001

 CO (L/min)

6225 ± 982

5619 ± 1410

0.029

 CI (L/min/m2)

2921 ± 390

2846 ± 643

0.571

 EF (%)

54.8 ± 8.7

56.2 ± 7.9

0.016

 E/A-peak ratio

0.95 ± 0.28

1.08 ± 0.27

0.063

 E deceleration (mL/s² x 10-³)

−2.20 ± 0.96

−1.87 ± 0.53

0.108

 E/Ea

8.9 ± 5.0

6.6 ± 4.4

0.076

  1. Data are mean ± SD, n = 27. p value before vs. after VLCD based on a paired sample t-test
  2. A diastolic atrial contraction, CO cardiac output, CI cardiac index, E early diastolic filling phase, EDV end-diastolic volume, E/Ea estimate of LV filling pressure, EF ejection fraction, ESV end-systolic volume, I indexed for body surface area, LV left ventricular, SV stroke volume
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