Fig. 4: Glucose utilization index (GUI) of white adipose tissues (WAT) under a high (18 mUI/kg/min) (left panel) and a low (9 mUI/kg/min) (right panel) insulin dose during hyperinsulinemic-euglycemic clamp at day 7–8 of refed on a low-fat or high-fat diets.

LF low fat, HF SMFA high-fat saturated monounsaturated fatty acids, HF ePUFA high-fat essential polyunsaturated fatty acids, EWAT epididymal white adipose tissue, IWAT inguinal white adipose tissue, MWAT mesenteric white adipose tissue, RWAT retroperitoneal white adipose tissue. Values are means ± SE (n = 7-9). Data are analyzed by one-way analysis of variance (ANOVA) (***p < 0.001) followed by post hoc pairwise comparisons using Scheffe’s test. Values not sharing a common superscript letter are significantly different at p < 0.05.