Table 3 Metabolic responses to infant formulas, varying in type and quantity of protein, and human milk.

From: Comparison of the acute metabolic effect of different infant formulas and human milk in healthy adults: a randomized trial

 

INTACT n = 29

PHw n = 29

HPPHW n = 28

HM n = 8

Insulin, μIU/ml

iAUC

11.79

(6.56)

11.92

(7.13)

18.66

(11.62)

13.10

(6.41)

Cmax

40.88

(26.55)

40.29

(25.94)

57.24

(29.26)

43.36

(22.73)

Glucose, mmol/l

iAUC

0.24

(0.21)

0.24

(0.25)

0.45

(0.39)

0.40

(0.28)

Cmax

5.83

(0.92)

5.86

(1.02)

6.25

(0.87)

6.14

(0.63)

Active GLP-1, pmol/l

iAUC

5.28

(3.46)

3.80

(2.28)

4.62

(2.48)

2.55

(1.24)

C-peptides, ng/ml

iAUC

0.84

(0.65)

0.83

(0.62)

1.34

(1.03)

0.90

(0.54)

Glucagon, pg/ml

iAUC

5.31

(7.16)

4.04

(5.44)

4.01

(5.78)

2.31

(3.79)

Triglycerides, mol/l

iAUC

189.8

(175.8)

183.2

(116.5)

291.6

(162.2)

181.4

(131.1)

Free fatty acids, μmol/l

nAUC

−143.4

(107.2)

−150.1

(123.0)

−165.8

(136.8)

−187.1

(102.1)

Essential AA, mol/l

iAUC

116.2

(26.4)

86.7

(28.7)

156.8

(58.0)

93.3

(37.9)

  1. Values are mean (±standard deviation).
  2. INTACT intact protein formula, PHw partially hydrolyzed whey protein formula, HPPHW formula; HM human milk, iAUC incremental area under the curve, nAUC negative area under the curve, Essential AA essential amino acids.