Table 2 Effect of NAC supplementation on histological observation of rat salivary glands.

From: N-acetylcysteine supplementation did not reverse mitochondrial oxidative stress, apoptosis, and inflammation in the salivary glands of hyperglycemic rats

 

C

C + NAC

HFD

HFD + NAC

Parotid glands

10 (+)

10 (+)

6 (++++), 4 (+++++)*

5 (++++), 5 (+++++)*

Submandibular glands

10 (+)

10 (+)

7 (++), 3 (+++)*

8 (++), 2 (+++)*

  1. C control rats C + NAC control rats + N-acetylcysteine, HFD rats fed the high-fat diet, HFD + NAC rats fed the high-fat diet + N-acetylcysteine, + single vacuoles in the cytoplasm of salivary acinar cells, ++ 5–10% of each section occupied by pathological alternations, +++ 11–20% of each section occupied by pathological alternations, ++++ 21–30% of each section occupied by pathological alternations, +++++ >30% of each section occupied by pathological alternations.
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