Table 3 Cox regression analysis for comparing the risk of all-cause and cardiovascular mortality between groups of low MIND diet score and high MIND diet score in T2DM and non-DM cohorts.

Model	HR (95% CI)				P-value¹	P-value²
Model	MIND diet score-L/non-DM	MIND diet score -H/non-DM	MIND diet score -L/DM	MIND diet score -H/DM	P-value¹	P-value²
All-cause mortality
Number of deaths/totals	436/3265	313/2601	214/581	124/440
Crude	Ref [1]	0.83 (0.67, 1.03)	Ref [2]	0.73 (0.56, 0.95)	0.093	0.020
Model 1	Ref [1]	0.63 (0.53, 0.77)	Ref [2]	0.64 (0.50, 0.83)	< 0.001	< 0.001
Model 2	Ref [1]	0.83 (0.67, 0.97)	Ref [2]	0.76 (0.60, 0.96)	0.021	0.022
Model 3	Ref [1]	0.83 (0.70, 0.99)	Ref [2]	0.75 (0.59, 0.96)	< 0.001	0.021
Cardiovascular mortality
Number of deaths/totals	143/3265	104/2601	88/581	42/440
Crude	Ref [1]	0.83 (0.64, 1.07)	Ref [2]	0.47 (0.26, 0.84)	0.146	0.011
Model 1	Ref [1]	0.62 (0.48, 0.81)	Ref [2]	0.43 (0.24, 0.78)	<0.001	0.005
Model 2	Ref [1]	0.81 (0.60, 1.10)	Ref [2]	0.49 (0.28, 0.86)	0.185	0.012
Model 3	Ref [1]	0.85 (0.62, 1.16)	Ref [2]	0.50 (0.29, 0.87)	0.309	0.014

Model 1: adjusted for age, sex, and race/ethnicity;
Model 2: further adjusted (from Model 1) for education level, family income to poverty ratio, smoking status, BMI, and physical activity;
Model 3: further adjusted (from Model 2) for hypertension, dyslipidemia, energy intake, and eGFR.
Low MIND score, the MIND score ≤ 8; High MIND score, the MIND score > 8.
HRs Hazard ratios, CIs Confidence intervals, MIND diet Mediterranean-DASH Diet Intervention for Neurodegenerative Delay diet, DM Diabetes mellitus, BMI Body mass index, eGFR Estimated glomerular filtration rate, Ref Reference, P value¹: The P value between MIND diet score-Low/non-DM and MIND diet score-High/non-DM groups. P value²: The P value between MIND diet score-Low/DM and MIND diet score-High/DM groups.

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