Table 2 Comparison between children and adolescents with T1DM and controls regarding various clinico-laboratory parameters.

From: Magnesium, fibrinolysis and clotting interplay among children and adolescents with type 1 diabetes mellitus; potential mediators of diabetic microangiopathy

  

Children and adolescents with T1DM

Control

  
  

(n=46)

(n=46)

Test

p value

Gender

Male

21 (45.7%)

18 (39.1%)

X2=0.41

0.520

 

Female

25 (54.3%)

28 (60.9%)

  

Age (years)

Mean ± SD

13.7±3.1

12.9±2.9

t=0.98

0.260

 

Range

8–18

7–18

  

Clinical:

     

MDQ-10

Deficiency

13 (28.3%)

0 (0.0%)

X2=15.1

<0.001*

Tingling

Positive

10 (21.7%)

0 (0.0%)

X2=11.2

<0.001*

Muscle cramps

Positive

12 (26.1%)

0 (0.0%)

X2=13.8

<0.001*

Laboratory:

     

Magnesium (mg/dL)

Mean ± SD

1.3 ±0.1

2.0 ±0.2

1.7-2.4

t=20.8

<0.001*

 

Range

0.6-1.5

   

PT (seconds)

Mean ± SD

11.1 ±0.2

12.3 ±0.3

12-13

t=21.6

<0.001*

 

Range

7–11.5

   

APTT (seconds)

Mean ± SD

21.2 ±1.9

31.1 ±2.7

25-35

t=17.6

<0.001*

 

Range

15–24

   

PAI-I (ng/ml)

Mean ± SD

10.3 ±4.9

2.8 ±1.3

1.5-10.5

t=9.95

<0.001*

 

Range

3.7–24

   

Cholesterol (mg/dl)

Mean ± SD

173.0 ±41.6

101.9 ±10.7

85.0-123.0

t=11.23

<0.001*

 

Range

122.0–270.0

   

Triglycerides (mg/dl)

Mean ± SD

92.1 ±33.8

66.4 ±18.3

40.0-91.0

t=4.53

<0.001*

 

Range

40.0–166.0

   

HDL (mg/dl)

Mean ± SD

55.3 ±14.9

67.4 ±8.11

t=-4.81

<0.001*

 

Range

31.0–87.0

54.0-84.0

  

LDL-c (mg/dl)

Mean ± SD

100.9 ±23.1

81.5 ±14.1

t=4.84

<0.001*

 

Range

60.0-160.0

65.0-110.0

  
  1. X2: Chi square test, t: Student t-test, Bold and asterisk (*): significant.
  2. T1DM Type 1 diabetes mellitus, MDQ-10 magnesium deficiency questionnaire-10, HDL high-density lipoproteins, LDL-c low density lipoproteins, PTprothrombin time, aPTT activated partial thromboplastin time, PAI-1 plasminogen activator inhibitor-1.
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