Table 4 Comparison between children and adolescents with T1DM with and without vascular complications regarding various clinico-laboratory parameters.

From: Magnesium, fibrinolysis and clotting interplay among children and adolescents with type 1 diabetes mellitus; potential mediators of diabetic microangiopathy

  

Children and adolescents with T1DM

  
  

With vascular complications (n=17)

Without vascular complications (n=29)

Test

P value

Symptoms of magnesium deficiency

     

MDQ-1

Deficiency

7

38.9%

6

21.4%

X2=2.6

0.019*

Tingling

Positive

6

33.3%

4

14.3%

X2=2.2

0.012*

Muscle cramps

Positive

8

44.4%

4

14.3%

X2=5.1

<0.001*

Laboratory parameters

     

Magnesium (mg/dL)

Mean ± SD

0.9±0.1

1.3±0.1

t=14.1

<0.001*

 

Range

0.7-1.0

1.2-1.5

  

PT (seconds)

Mean ± SD

8.2±2.0

11.0±0.3

t=7.3

<0.001*

 

Range

7-10

10-11.5

  

aPTT (seconds)

Mean ± SD

15.7±0.8

21.3±1.8

t=12.3

<0.001*

 

Range

15-18

18-24

  

PAI-I (ng/ml)

Mean ± SD

11.0±5.2

9.3±4.3

t=4.6

<0.001*

 

Range

4-21

3.7-24

  
  1. X2: Chi square test, t: Student t-test, MDQ-10 magnesium deficiency questionnaire-10, PT Prothrombin time, aPTT Activated Partial Thromboplastin Time, PAI-I Plasminogen Activator Inhibitor Type-1.
  2. Bold and asterisk (*): significant.
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