Fig. 3: SLC6A19 inhibits RCC metastasis via transporting tryptophan. | Oncogenesis

Fig. 3: SLC6A19 inhibits RCC metastasis via transporting tryptophan.

From: SLC6A19-mediated tryptophan uptake suppresses renal cell carcinoma metastasis via activating NAD+-dependent deacetylase SIRT1

Fig. 3: SLC6A19 inhibits RCC metastasis via transporting tryptophan.

A, B Transwell assays of 786-O and Caki-1 cell lines with overexpression of SLC6A19 and removal of tryptophan in vitro. C, D Wound-healing assays of 786-O and Caki-1 cell lines with overexpression of SLC6A19 and removal of tryptophan in vitro. E Protein expression of EMT-related cellular markers and transcription factors in cell lines. Scale bar = 50 μm ***p < 0.001, ****p < 0.0001.

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