Table 1 Correlation of SLC6A19 expression to clinicopathological features in RCC patients.

From: SLC6A19-mediated tryptophan uptake suppresses renal cell carcinoma metastasis via activating NAD+-dependent deacetylase SIRT1

Variables

 

SLC6A19

P value

Low

High

Gender

Male

37

32

0.759a

Female

23

24

Age, y

≤50

24

23

1.000a

>50

36

33

Histological grade

1

21

32

<0.001a

2

7

14

3 + 4

32

10

T stage

T1

18

43

<0.0001a

T2

13

9

T3 + T4

29

4

N stage

N0

54

53

0.493b

N1

6

3

Distant metastasis

M0

45

52

0.012b

M1

15

4

Recurrence

No

56

55

0.366b

Yes

4

1

Histological subtype

ccRCC

52

45

0.889b

pRCC

6

5

chRCC

5

3

  1. The TNM stage grouping was determined based on the AJCC 2017 TNM staging classification system.
  2. ccRCC Clear cell renal cell carcinoma, pRCC Papillary renal cell carcinoma, chRCC Chromophobe renal cell carcinoma.
  3. aChi-square test.
  4. bFisher’s exact test was employed to assess statistical significance.