Fig. 1: YTHDF3 expression in primary and metastatic breast cancer lesions and the relationship with prognosis. | Oncogenesis

Fig. 1: YTHDF3 expression in primary and metastatic breast cancer lesions and the relationship with prognosis.

From: YTHDF3 promotes breast cancer osteolytic bone metastasis by enhancing the translation of ZEB1 and SMAD5

Fig. 1

A Comparison of YTDHF3 expression in breast cancer tissues and paracancer tissues using TCGA database data. B Comparison of YTDHF3 expression in primary breast cancer lesions and metastatic tissues using GEO microarray data. C Representative images of IHC showing the YTHDF3 expression in breast cancer paracancer tissues, primary breast cancer foci tissue, and the results of H-score statistical analysis. D IHC image of YTHDF3 expression in primary breast cancer tissue and matched bone metastasis lesion. E YTHDF3 expression levels were negatively correlated with overall survival of breast cancer patients. F YTHDF3 expression was negatively correlated with metastasis-free survival and bone metastasis free survival of breast cancer patients. G YTHDF3 expression in different breast cancer cell lines. H YTHDF3 expression in 231 cells and its metastatic subtypes (231-HM: highly metastatic cell line; 231-BO: bone metastasis subtype).

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