Fig. 4: Serum MMP7 overexpressed in BA patients and derived from cholangiocytes.

a Immunofluorescence co-staining of MMP7 (green) and CK19 (red) in BA liver tissues. Nuclei were counterstained with DAPI (blue). White arrows indicate co-localized signals (scale bar: 20 μm). b MMP7 levels in serum of BA and non-BA jaundiced patients. c Correlation heatmap of preoperative serum MMP7 with clinical indicators in BA patients. d MMP7 levels in serum of pre- and post-operative BA patients. e Correlation heatmap of postoperative serum MMP7 with clinical indicators in BA patients. (****p < 0.0001). DAPI 4′,6-Diamidino-2-Phenylindole.