Fig. 3: Histograms of where each of the nine target genes fell in each of the three analyses.

The x axis is the difference between group means and the y axis represents the percentage of the 8155 genes analyzed with that value for a difference between group means. The bold vertical dashed lines represent the three standard deviation cut offs used in the analysis. Genes with negative values to the left are potentially protective and genes with positive values to the right are potentially detrimental. a is the analysis of all study participants, b is the subgroup analysis for discordant siblings and c is the analysis of unrelated participants. SD Standard Deviation.