Fig. 1: Altered levels of CD4+ and CD4+FOXP3+ (Treg) T cells in the peripheral blood across bronchiolitis severity groups.
From: Pediatric bronchiolitis disease severity is associated with immune checkpoint dysregulation
a Representative flow cytometry plots showing the gating strategy for lymphocyte and CD4⁺FOXP3⁺ T cell identification: lymphocytes were gated using SSC-A versus FSC-A, followed by gating on CD4⁺ cells and FOXP3 expression analysis. b Percentages of CD4⁺ T cells. c Absolute numbers of CD4⁺ T cells. d Percentages of CD4⁺FOXP3⁺ T cells. e Absolute numbers of CD4⁺FOXP3⁺ T cells. Statistical analysis was conducted for 151 children (40 control, 40 mild, 40 moderate, and 31 severe bronchiolitis). (*P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001). Error bars represent ± SEM.
