Table 3 The univariate and multivariate association of year of treatment and use of very high dose (>7020 cGy) post-operative radiation in the treatment of prostate cancer
<7020 cGy | >7020 cGy | Univariate | Multivariate | |||
|---|---|---|---|---|---|---|
OR (CI) | p-value* | OR (CI) | p-valuea | |||
Year of treatment | 1.05 (1.03–1.07) | <0.01 | 1.05 (1.03–1.08) | <0.01 | ||
Age, mean (range) | 60.6 (25–89) | 60.6 (38–85) | 1.01 (1.00–1.02) | 0.06 | 1.01 (1.00–1.02) | 0.05 |
Pathologic stage, No (%) | 0.86 (0.76–0.99) | 0.03 | 0.82 (0.72–0.95) | <0.01 | ||
T2 | 3266 (27.1) | 348 (30.0) | ||||
T3 | 8770 (72.9) | 811 (70.0) | ||||
Gleason score, No (%) | 0.93 (0.86–1.00) | <0.01 | 0.94 (0.86–1.00) | 0.19 | ||
≤6 | 1165 (9.7) | 118 (10.2) | ||||
7 | 5793 (48.1) | 561 (48.4) | ||||
8–10 | 4021 (33.4) | 414 (35.7) | ||||
Missing | 1057 (8.8) | 66 (5.7) | ||||
Pre-surgical PSA, No (%) | 0.96 (0.90–1.00) | 0.01 | 1.00 (0.94–1.06) | 0.93 | ||
<10 ng/ml | 7190 (59.7) | 711 (61.3) | ||||
10–20 ng/ml | 2053 (17.1) | 182 (15.7) | ||||
>20 ng/ml | 1358 (11.3) | 154 (13.3) | ||||
Missing | 1435 (11.9) | 112 (9.7) | ||||
Surgical margins, No (%) | 0.95 (0.83–1.08) | 0.45 | 0.94 (0.82–1.07) | 0.41 | ||
Positive | 8054 (66.9) | 763 (65.8) | ||||
Negative | 3982 (33.1) | 396 (34.2) | ||||
Hormone therapy, No (%) | 1.13 (1.01–1.26) | 0.03 | 1.19 (1.06–1.33) | <0.01 | ||
Yes | 3498 (29.1) | 380 (32.8) | ||||
No | 8219 (68.3) | 749 (64.6) | ||||
Unknown | 319 (2.7) | 30 (2.6) | ||||
Race, No (%) | 0.96 (0.85–1.08) | 0.42 | 0.97 (0.86–1.10) | 0.50 | ||
White | 9857 (81.9) | 962 (83.0) | ||||
Black | 1625 (13.5) | 141 (12.2) | ||||
Other | 554 (4.6) | 56 (4.8) | ||||
Hispanic origin, No (%) | 1.06 (0.96–1.16) | 0.49 | 1.07 (0.97–1.18) | 0.11 | ||
Spanish | 525 (4.4) | 54 (4.7) | ||||
Non-Spanish | 10411 (86.5) | 988 (85.2) | ||||
Unknown | 1100 (9.1) | 117 (10.1) | ||||
Charlson–Deyo score, No (%) | 1.03 (0.89–1.18) | 0.01 | 1.00 (0.87–1.15) | 0.92 | ||
0 | 10192 (84.7) | 966 (83.3) | ||||
1 | 1624 (13.5) | 181 (15.6) | ||||
2+ | 220 (1.8) | 12 (1.0) | ||||
Facility type, No (%) | 0.90 (0.82–0.99) | <0.01 | 0.90 (0.82–1.00) | 0.05 | ||
Community and other | 1342 (11.1) | 114 (9.8) | ||||
Comprehensive | 6807 (56.6) | 730 (63.0) | ||||
Academic | 3887 (32.3) | 315 (27.2) | ||||
Hospital setting, No (%) | 0.96(0.81–1.14) | 0.69 | . | . | ||
Metro | 9828 (81.6) | 950 (82.0) | ||||
Non-metro | 1862 (15.5) | 174 (15.0) | ||||
Missing | 346 (2.9) | 35 (3.0) | ||||
Facility location, No (%) | 1.03 (0.97–1.01) | 0.25 | ||||
East | 4587 (38.1) | 430 (37.1) | ||||
West | 2339 (19.4) | 240 (20.7) | ||||
Central north | 3702 (30.8) | 349 (30.1) | ||||
Central south | 1408 (11.7) | 140 (12.1) | ||||
Insurance status, No (%) | 0.99(0.95–1.04) | 0.46 | 0.97 (0.92–1.03) | 0.34 | ||
No insurance | 220 (1.8) | 20 (1.7) | ||||
Private | 7699 (64) | 733 (63.2) | ||||
Medicaid | 310 (2.6) | 28 (2.4) | ||||
Medicare | 3405 (28.3) | 350 (30.2) | ||||
Other | 223 (1.9) | 15 (1.3) | ||||
Unknown | 179 (1.5) | 13 (1.1) | ||||
Median income, No (%) | 0.94 (0.88–0.99) | 0.05 | 0.93 (0.88–0.99) | 0.03 | ||
<38,000 | 1690 (14.2) | 173 (15.1) | ||||
38,000–47,999 | 2542 (21.4) | 279 (24.4) | ||||
48,000–62,999 | 3364 (28.3) | 307 (26.9) | ||||
>63,000 | 4281 (36) | 383 (33.5) | ||||
