Table 1 Data on clinical parameters by PSA group.

From: Clinical use of the mRNA urinary biomarker SelectMDx test for prostate cancer

PSA group

PSA < 3 ng/mL

PSA ≥ 3 and ≤ 10 ng/mL

PSA > 10 and ≤ 15 ng/mL

PSA > 15 ng/mL

All PSA levels

N (% of total)

275 (5.33)

3953 (76.65)

579 (11.23)

350 (6.79)

5157 (100)

Age median, years (Q1–Q3)

62 (54–68)

65 (59–70)

67 (62–72)

67 (62–72)

65 (60–71)

PSA median, ng/mL (Q1–Q3)

1.98 (1.22–2.5)

6.1 (4.88–7.66)

12 (11–13.15)

20 (16.94–24.9)

6.60 (4.90–9.06)

PV median, cm3 (Q1–Q3)a

37.5 (30–49.25)

50 (38–66)

62.35 (47–88.11)

65 (46.5–100)

51 (38–70)

PSA density median, ng/ml2 (Q1–Q3)a

0.05 (0.03–0.06)

0.12 (0.09–0.17)

0.19 (0.13–0.28)

0.31 (0.21–0.50)

0.13 (0.09 – 0.19)

DRE result: abnormal %, normal %

29.82; 70.18

15.79; 84.21

19.69; 80.31

28.29; 71.71

17.82; 82.18

RNA score median (Q1–Q3)

27 (14–68.50)

37 (20–71.26)

40 (22–79)

45 (26–85.50)

37.46 (20–73)

SelectMDx result: positive, N (%); negative, N (%);

68 (24.73); 207 (75.27)

2188 (55.35); 1765 (44.65)

467 (80.66); 112 (19.34)

334 (95.43); 16 (4.57)

3057 (59.28); 2100 (40.72)

  1. aProstate volume and therefore PSA density are unknown for 94 patients.