Table 2 OS in general, comparison by race.

From: The impact of race on survival in metastatic prostate cancer: a systematic literature review

Study

Populationa

Type of analysis/results

Whiteb

Blackc

Asiand

Hispanice

AI/ANf

HR (95% CI), p value

Bernard (2017) [22]

mCSPC

Log rank

Reference

p = 0.057

p < 0.001 g

p < 0.001 h

p = 0.398

Zhang (2021) [38]

mCSPC

Multivariable

Reference

1.02 (0.96–1.08), p = 0.50

0.73 (0.67-0.81), p < 0.0001

0.94 (0.88-1.01), p = 0.07

1.04 (0.81–1.32), p = 0.8

Weiner (2021) [36]

mCSPC

Multivariable

Reference

1.02 (0.88–1.18), p = 0.811

NR

0.97 (0.73–1.27), p = 0.809

NR

Weiner (2020) [35]

mCSPC

Multivariable

Reference

0.96 (0.91–1.00), p = 0.073

NR

0.78 (0.71–0.85), p < 0.001

NR

Vengaloor (2020) [34]

mCSPC (specifically bone metastases)

Multivariable

Reference

0.99 (0.95–1.04), p = NR

NR

NR

NR

mCSPC (specifically brain, liver, or lung metastases)

Multivariable

Reference

1.00 (0.79, 1.24), p = NR

NR

NR

NR

Garje (2020) [25]

mCSPC

Multivariable

Reference

0.98 (0.94–1.03), p = 0.43

NR

NR

NR

Keating (2019) [27]

mCSPC

Multivariable

Reference

1.03 (0.98–1.07), p = 0.2547

NR

0.96 (0.9–1.03), p = 0.2601

NR

Parikh (2017) [30]

mCSPC

Multivariable

Reference

0.97 (0.88–1.06), p = 0.50

NR

NR

NR

Oehrlein (2022) [41]

Mixed

Multivariable

Reference

0.68 (0.24–1.95), p = 0.476

NR

NR

NR

Ng (2021) [62]

mCRPC

Log rank

Reference

0.81 (0.64–1.03), p = 0.08

NR

NR

NR

Gupta (2021) [71]

mCRPC

Multivariable

Reference

1.67 (1.05–2.65), p = 0.03

NR

NR

NR

Akinyemiju (2018) [20]

mCSPC

Multivariable

Reference

1.03 (0.95–1.12), p = NR

NR

1.00 (0.91–1.10), p = NR

NR

Lec (2020) [49]

mCSPC

Multivariable

Referencei

1.08 (1.01–1.15), p = NR

NR

NR

NR

Zhao (2019) [51]

mCSPC

Multivariable

Reference

1.00 (0.94–1.05), p = 0.901

0.72 (0.65-0.80), p < 0.001

NR

NR

Powell (2014) [60]

mCSPC

Univariable

Reference

p = 0.8399

NR

NR

NR

Moreira (2017) [55]

mCRPC

Multivariable

Referencej

0.85 (0.59–1.22), p = 0.381

NR

NR

NR

Rusthoven (2016) [56]

mCSPC

Multivariable

Reference

1.11 (1.03–1.20), p = 0.008

NR

NR

NR

Schmid (2015) [57]

Mixed

Multivariable

Reference

0.94 (0.87–1.01), p = 0.865

NR

0.93 (0.83–1.04)k

NR

Sammon (2015) l [58]

Mixed

Multivariable

Reference

1.04 (0.74–1.44), p = 0.84

NR

1.28 (0.86–1.9), p = 0.23

NR

Farooq (2022) [70]

mCSPC

Univariable

Reference

0.99 (0.96–1.03), p = 0.71

NR

NR

NR

NR

1.048 (0.91, 1.21), p = 0.539

NR

NR

Reference

Jogerst (2020) [78]

mCSPC

NR

Reference

p < 0.001 m

NR

NR

NR

Guo (2018) [54]

mCSPC

Multivariable

Reference

1.13 (1.01–1.26), p = 0.03

0.77 (0.40–1.48), p = 0.43

NR

0.73 (0.58–0.91), p = 0.01

Becker (2019) [53]

mCRPC

Multivariable

Reference

2.21 (1.28–3.82), p = NR

NR

NR

NR

Smith (2021) [33]

mCSPC

Multivariable

Referencej

1.11 (0.51–2.40), p = 0.794

NR

NR

NR

Patel (2020) [48]

mCRPC

Multivariable

Referencej

0.87 (0.73–1.04), p = 0.13

NR

NR

NR

Patel (2018) [31]

mCRPC

Multivariable

Referencej

0.91 (0.73–1.12), p = NR

NR

NR

NR

Mazzone (2019) [52]

mCSPC

Multivariable

0.75 (0.54–1.04), p = 0.09

Reference

NR

NR

NR

  1. AI/AN American Indian and Alaska Native, CI confidence interval, HR hazard ratio, mPC metastatic prostate cancer, mCRPC metastatic castration resistant prostate cancer, mCSPC metastatic castration sensitive prostate cancer, NR not reported, OS overall survival.
  2. amCSPC and mCRPC population was assessed based on clinical judgement in instances that population was not explicitly stated in the text
  3. bColumn includes results for populations such as White, Non-Hispanic White, etc.
  4. cColumn includes results for populations such as Black, Non-Hispanic Black, etc.
  5. dColumn includes results for population such as Asian, Non-Hispanic Asian, Asian/Pacific Islander, etc.
  6. eColumn includes results for populations such as Hispanic, Hispanic (all races), Hispanic (White), etc.
  7. fColumn includes results for population such as AI/AN, Native American, etc.
  8. gAsian patients had statistically significant improved OS compared to White patients.
  9. hHispanic patients had statistically significant improved OS compared to White patients.
  10. iResults specifically for patients who lived longer than 2 years.
  11. jNon-Black.
  12. kp value was omitted due to inconsistent reporting in primary publication.
  13. lResults shown for in-hospital mortality.
  14. mBlack patients have statistically significant lower OS rates compared to White patients.
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