Table 1 Patient characteristics.

From: A non-invasive 25-Gene PLNM-Score urine test for detection of prostate cancer pelvic lymph node metastasis

 

IND-CHTN Retrospective Cohort

Multi-Hospital Prospective Cohort

No of patients

413

243

Median age (Q1, Q3)

65 (61, 68)

70 (64, 76)

ISUP/Gleason grade group (%)

 Group 1: ≤6 ( ≤ 3 + 3)

76 (18%)

56 (23%)

 Group 2: 7 (3 + 4)

197 (48%)

47 (19%)

 Group 3: 7 (4 + 3)

113 (27%)

63 (26%)

 Group 4: 8 (4 + 4, 3 + 5, 5 + 3)

9 (2%)

43 (18%)

 Group 5: 9 or 10 (4 + 5, 5 + 4, or 5 + 5)

18 (4%)

34 (14%)

Pre-operative PSA (%)

 PSA < 10 ng/dL

0

84 (35%)

 PSA 10-20 ng/dL

0

53 (22%)

 PSA > 20 ng/dL

0

104 (43%)

 PSA unknown

413 (100%)

2 (0.8%)

Pelvic lymph node metastasis (%)

20 (5%)

35 (14%)

Median number of lymph nodes dissected (Q1, Q3)

6 (4, 10)

13 (9, 15)

Distant metastasis (%)

9 (2%)

76 (31%)

BCR (%)

42 (10%)

-

Cancer risk (%)

 Low risk

42 (10%)

29 (12%)

 High risk

371 (90%)

214 (88%)

  1. PSA prostate specific antigen, BCR biochemical recurrence.