Fig. 4: OS after BCR among patients with nmCSPC by PSADT cohort including historical Johns Hopkins data.

Includes historical overall survival data of patients with BCR after radical prostatectomy from Freedland et al. 2007 [4]. The adjusted Cox proportional hazards models adjusted for patient demographics and clinical characteristics including age, age group (<60 [reference], 60–69, 70–79, and ≥80 years), race (White [reference], Black, Hispanic, and other), log(time from definitive therapy to index date), log(index PSA), modified Charlson Comorbidity Index, and index year (2006–2016 vs. 2017–2020). *P-value ≤ 0.05. BCR biochemical recurrence; CI confidence interval; HR hazard ratio; nmCSPC nonmetastatic castration-sensitive prostate cancer; OS overall survival; PSA prostate-specific antigen; PSADT PSA doubling time.