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Clinical

Prostate cancer screening and management in patients candidate for endoscopic enucleation of the prostate: an international survey

Abstract

Background

To explore how urologists manage prostate cancer (PCa) screening and treatment in patients undergoing endoscopic enucleation of the prostate (EEP).

Methods

A team of experts in EEP collaboratively formulated the survey questions through an interactive process. The survey opened in January 2024 and closed in February 2024.

Results

102 urologists responded, revealing that most use PSA and digital rectal examination for screening, with high PSA and abnormal DRE prompting prostate MRI. 75% perform pre-EEP biopsies. For incidental low-grade PCa, active surveillance is preferred. For intermediate-grade PCa, most use PSA and MRI for workup, often choosing active surveillance if post-EEP biopsies are negative. There’s no consensus on abnormal post-operative PSA thresholds.

Conclusions

While urologists are aware of PCa management in EEP candidates, future work should focus on developing optimal post-EEP screening protocols.

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Authors and Affiliations

Authors

Contributions

AU: Project development, data collection, data analysis, and manuscript drafting. JNC: project development, critical revision of the manuscript; BP: project development, critical revision of the manuscript; TRWH: project development, critical revision of the manuscript; VM: project development, critical revision of the manuscript; MR: critical revision of the manuscript; CDN: project development, critical revision of the manuscript; HH: project development, critical revision of the manuscript; GP: project development, critical revision of the manuscript; MB project development, data analysis, drafting of the manuscript.

Corresponding author

Correspondence to Alessandro Uleri.

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Competing interests

The authors have nothing to disclose. Alessandro Uleri had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

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Uleri, A., Cornu, J.N., Pradere, B. et al. Prostate cancer screening and management in patients candidate for endoscopic enucleation of the prostate: an international survey. Prostate Cancer Prostatic Dis 28, 837–839 (2025). https://doi.org/10.1038/s41391-024-00909-w

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