Table 2 Oncological outcomes of the patients who were treated with focal therapy with high-intensity focused ultrasound.

From: Focal therapy using high-intensity focused ultrasound with intraoperative prostate compression for patients with localized prostate cancer: a multi-center prospective study with 7 year experience

 

Low-risk groupa (n = 51)

Intermediate-risk group (n = 107)

High-risk group (n = 82)

P-value

Nadir value of serum PSA level (ng/mL)

1.52 (0.10–4.86)

1.11 (0.07–8.97)

1.14 (0.04–11.56)

0.235

Decreased rates of serum PSA level

73% (7.0–99)

81% (22–99)

83% (14–99)

0.034

Biochemical failure free-survival ratesb

92.2%

89.7%

85.4%

0.443

Pathological failure free-survival rates

93.7%

91.6%

86.6%

0.445

Rates of pathological recurrence in treated area

0% (0 cases)

0% (0 cases)

0% (0 cases)

-

No. of repeat focal therapy of the patients with pathological failure

3.9% (2 cases)

4.7% (5 cases)

2.4% (2 cases)

0.724

Radical or systematic treatment free rates

96.1%

94.4%

95.1%

0.900

Follow-up periods (months)

54 (24–84)

48 (24–84)

48 (24–84)

0.004

  1. PSA prostate specific antigen.
  2. aD’Amico risk classification.
  3. bPhoenix ASTRO definition.