Fig. 7 | Signal Transduction and Targeted Therapy

Fig. 7

From: Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation

Fig. 7The alternative text for this image may have been generated using AI.

DC551040 combination with HHT synergistically enhances the treatment of AML. The synergistic effect of different concentrations of HHT and DC551040 was detected in MV-4-11 cells (a), MOLM-13 cells (b), Kasumi-1 cells (c) and HL60 cells (d), and the synergistic ability was calculated using the ZIP algorithm. The synergistic effect of different concentrations of C188-9 and DC551040 was detected in MV-4-11 cells (e), MOLM-13 cells (f), Kasumi-1 cells (g) and HL60 cells (h), and the synergistic ability was calculated using the ZIP algorithm. All data of this figure are represented as mean ± SEM, n = 3 per group

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