Fig. 2: Associations between preoperative SF levels and POD risk on continuous scales.

A Unadjusted model. B Multivariable model adjusted for age, sex, BMI, NLR, TBil, ALT, cancer, diabetes mellitus, and renal insufficiency. C Multivariable model additionally adjusted for Hb levels as a potential mediator. ORs are indicated by red solid lines and 95% CIs by dark gray dotted lines. Reference lines for no association are indicated by the gray dotted lines at an OR of 1.0. Density plots are presented by gray shadow area to show the fraction of the population with different levels of log10 SF. The log10 SF level corresponding to the OR equal to 1 (reference value) is shown by dark spot. SF, serum ferritin; POD, postoperative delirium; BMI, body mass index; NLR, neutrophil-to-lymphocyte ratio; TBil, total bilirubin; ALT, alanine aminotransferase; Hb, hemoglobin; OR, odds ratio; CI, confidence interval; SD, standard deviation.