Table 1 Baseline characteristics by preoperative SF quintiles.

From: Preoperative serum ferritin as a biomarker for predicting delirium among elderly patients receiving non-cardiac surgery: a retrospective cohort study

 

Overall

Preoperative SF levels (μg/L)

p-value

Quintile 1 (≤51.81)

Quintile 2 (51.81–110.10)

Quintile 3 (110.10–180.70)

Quintile 4 (180.70–307.90)

Quintile 5 (>307.90)

n

12,841

2569

2571

2567

2566

2568

 

SF; μg/L

142.10 (65.63–266.40)

24.30 (14.31–37.23)

81.17 (65.67–95.55)

142.20 (126.10–159.40)

232.15 (203.83–266.70)

461.80 (369.42–673.20)

<0.001

log10 SF

2.10 (0.49)

1.34 (0.27)

1.90 (0.09)

2.15 (0.06)

2.37 (0.07)

2.72 (0.20)

<0.001

Demographics

 Age; years

70 (67–75)

71 (67–75)

70 (67–75)

70 (67–74)

70 (67–75)

70 (67–74)

<0.001

 Male

7903 (61.5%)

1584 (61.7%)

1346 (52.4%)

1506 (58.7%)

1649 (64.3%)

1818 (70.8%)

<0.001

 BMI; kg/m2

24.12 (3.43)

24.03 (3.52)

24.09 (3.38)

24.34 (3.40)

24.33 (3.38)

23.79 (3.43)

<0.001

Preexisting comorbidities

 Renal insufficiency

299 (2.3%)

35 (1.4%)

40 (1.6%)

50 (1.9%)

81 (3.2%)

93 (3.6%)

<0.001

 Diabetes mellitus

3152 (24.5%)

669 (26.0%)

634 (24.7%)

604 (23.5%)

574 (22.4%)

671 (26.1%)

0.006

 Cancer

7659 (59.6%)

1762 (68.6%)

1546 (60.1%)

1488 (58.0%)

1425 (55.5%)

1438 (56.0%)

<0.001

 Anemia

3265 (25.4%)

1397 (54.4%)

418 (16.3%)

310 (12.1%)

406 (15.8%)

734 (28.6%)

<0.001

Baseline laboratory examination

 Hb; g/L

126.00 (19.26)

112.47 (20.03)

127.91 (16.17)

131.68 (15.67)

131.52 (17.07)

126.42 (20.13)

<0.001

 NLR

2.07 (1.53–2.96)

2.14 (1.59–3.05)

1.97 (1.46–2.67)

1.94 (1.47–2.68)

2.03 (1.52–2.91)

2.37 (1.70–3.65)

<0.001

 TBil; μmol/L

15.82 (30.32)

9.59 (7.26)

11.13 (7.02)

12.03 (9.49)

13.71 (17.63)

32.62 (61.11)

<0.001

 ALT; U/L

20.76 (29.76)

13.72 (13.35)

15.46 (12.07)

17.73 (21.15)

20.49 (26.32)

36.43 (51.32)

<0.001

Operation related variables

 Emergency surgery

399 (3.1%)

60 (2.3%)

48 (1.9%)

72 (2.8%)

74 (2.9%)

145 (5.6%)

<0.001

 Surgery specialty

      

<0.001

 Obstetrics/Gynecology

138 (1.1%)

16 (0.6%)

22 (0.9%)

35 (1.4%)

35 (1.4%)

30 (1.2%)

 

 Hepatobiliary/Pancreatic/Gastrointestinal

7248 (56.4%)

2109 (82.1%)

1456 (56.6%)

1267 (49.4%)

1151 (44.9%)

1265 (49.3%)

 

 Orthopedic

747 (5.8%)

66 (2.6%)

135 (5.3%)

183 (7.1%)

168 (6.5%)

195 (7.6%)

 

 Urology

1185 (9.2%)

102 (4.0%)

211 (8.2%)

276 (10.8%)

303 (11.8%)

293 (11.4%)

 

 Thoracic

891 (6.9%)

67 (2.6%)

179 (7.0%)

230 (9.0%)

236 (9.2%)

179 (7.0%)

 

 Vascular

693 (5.4%)

44 (1.7%)

137 (5.3%)

157 (6.1%)

195 (7.6%)

160 (6.2%)

 

 Otorhinolaryngology—Head & Neck, Plastic, or Abdominal wall surgery

1421 (11.1%)

116 (4.5%)

359 (14.0%)

331 (12.9%)

373 (14.5%)

242 (9.4%)

 

 Endoscopic

518 (4.0%)

49 (1.9%)

72 (2.8%)

88 (3.4%)

105 (4.1%)

204 (7.9%)

 

 Surgery duration; hours

2.50 (1.53–3.50)

2.83 (2.00–3.67)

2.33 (1.47–3.33)

2.33 (1.45–3.33)

2.25 (1.42–3.42)

2.57 (1.45–3.75)

<0.001

Outcome

 POD

445 (3.5%)

111 (4.3%)

57 (2.2%)

65 (2.5%)

85 (3.3%)

127 (4.9%)

<0.001

  1. Values are mean (SD), number (proportion), or median (IQR).
  2. SF serum ferritin, BMI body mass index, Hb hemoglobin, NLR neutrophil-to-lymphocyte ratio, TBil total bilirubin, ALT alanine aminotransferase, POD postoperative delirium, SD standard deviation, IQR interquartile range.
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