Fig. 1: Diversity analysis of gut microbiota in two groups.

A Venn diagram—overlap of OTUs between responders and non-responders. B Boxplot of OTU abundance—comparison of OTU abundance between responders and non-responders. C Boxplot of OTU correlation—comparison of OTU correlation within and between groups. D Heatmap of OTU correlation—visual representation of OTU correlations within and between groups. E Boxplot of Chao Index—comparison of species richness between responders and non-responders. F Principal coordinates analysis (PCoA) plot—visualization of overall gut microbiota differences between responders and non-responders. G Distribution of genus species—comparison of the distribution of genus species in the two groups. H Differential analysis of species at the genus level—comparison of genus-level species differences between responders and non-responders. I Differences in species abundance at the genus level—Bar chart showing the differences in genus-level species abundance between the two groups.