Table 1 Demographic and clinical characteristics for all Participants.

From: Sex-specific habenular dysconnectivity in patients with late-life depression

Parameter

LLD

HCs

Interactive Effect of Diagnosis and Sex (F/P)

Main Effect of Diagnosis (F/P)

Main Effect of Sex (F/T/P)

Male

Female

Male

Female

(n = 26)

(n = 88)

(n = 24)

(n = 51)

Age (year)

68.27 ± 7.32

67.52 ± 7.00

67.96 ± 6.21

66.29 ± 5.67

0.173 (0.678)

0.779 (0.379)

0.928 (0.337)

Education (year)

10.13 ± 4.05

9.30 ± 3.21

10.46 ± 1.84

11.14 ± 2.61

2.209 (0.139)

9.893 (0.002)

0.372 (0.542)

HAMD-17

8.54 ± 8.72

9.22 ± 6.71

1.17 ± 1.27

1.61 ± 2.09

0.015 (0.902)

80.238 (<0.001)

1.619 (0.205)

MMSE

23.54 ± 4.72

23.78 ± 4.56

27.25 ± 1.54

27.29 ± 1.38

0.027 (0.870)

42.458 (<0.001)

0.137 (0.711)

AVLT N5

3.63 ± 3.03

4.37 ± 3.32

6.42 ± 2.21

7.31 ± 1.91

0.025 (0.875)

44.189 (<0.001)

0.715 (0.399)

WMT

4.32 ± 2.61

3.69 ± 2.54

7.23 ± 3.05

7.25 ± 2.67

0.464 (0.497)

62.462 (<0.001)

1.506 (0.222)

Stroop A (s)

36.00 ± 8.76

34.00 ± 12.12

30.32 ± 7.70

27.77 ± 7.18

0.024 (0.878)

13.394 (<0.001)

0.749 (0.388)

Stroop C (s)

92.55 ± 31.36

98.46 ± 39.02

82.19 ± 26.46

75.50 ± 19.48

1.204 (0.274)

13.985 (<0.001)

0.099 (0.753)

TMT B (s)

22.27 ± 1.49

21.83 ± 2.58

22.55 ± 0.80

22.73 ± 0.73

0.872 (0.352)

5.777 (<0.017)

0.423 (0.516)

VFT

7.58 ± 3.27

9.22 ± 4.70

11.08 ± 4.12

12.51 ± 3.63

0.022 (0.882)

25.479 (<0.001)

2.192 (0.140)

ROCF

25.48 ± 4.88

23.50 ± 6.85

28.68 ± 2.88

28.48 ± 3.10

0.888 (0.348)

29.352 (<0.001)

2.576 (0.111)

  1. LLD late-life depression, HCs healthy controls, HAMD-17 17-item hamilton depression scale, MMSE mini-mental state examination, AVLT N5 auditory verbal learning test long-term delayed recall, WMT working memory test, Stroop the stroop color and word test, TMT trail-making test, VFT verbal fluency test, ROCF rey-osterrieth complex figure.