Fig. 3: Gut microbiome analysis in resilient and susceptible male and female mice.

A, I Alpha diversity of resilient and susceptible male (n = 7 mice per group) A and female (n = 7–8 mice per group) I mice using Faith’s PD metric. B, J Beta diversity of resilient and susceptible male B and female J mice using unweighted UniFrac distance. C, K Beta diversity of resilient and susceptible male C and female K mice using Jaccard distance. D–M Three-dimensional principal coordinate analysis based on unweighted UniFrac and Jaccard distances in resilient and susceptible male D, E and female L, M mice. F, N Microbial distribution of relative abundance at the family level in resilient and susceptible male F and female N mice. G, O Bacterial groups enriched in resilient and susceptible male G and female O mice by using LEfSe analysis. H Enriched bacterial group in susceptible and resilient male mice by using ANCOM-BC analysis. *p < 0.05 (comparison between resilient and susceptible male mice).