Fig. 4: Transcriptome analysis in the amygdala of resilient and susceptible male and female mice. | Translational Psychiatry

Fig. 4: Transcriptome analysis in the amygdala of resilient and susceptible male and female mice.

From: Exploring individual differences in fear extinction in male and female mice: insights from HPA axis, microbiota, and transcriptomics

Fig. 4

A Schematic representation of the experimental design. B DEGs between resilient and susceptible male and female mice (n = 4 mice per group). C, G Principal component analysis in resilient and susceptible male C and female G mice. D, H Volcano plot summarizing DEGs of resilient and susceptible male D and female H mice. E DEGs in each resilient and susceptible male mouse clustered with a heat map. F Disease-gene association analysis using the DISEASES database reveals that 14 DEGs in susceptible male mice were previously associated with PTSD, anxiety, fear, or stress disorders. DEGs, differentially expressed genes.

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