Fig. 1: The association between SSRS and PRS for ASD in the ABCD study. | Translational Psychiatry

Fig. 1: The association between SSRS and PRS for ASD in the ABCD study.

From: Demographic, genetic, neuroimaging, and behavioral correlates of short social responsiveness scale in a large pediatric cohort

Fig. 1: The association between SSRS and PRS for ASD in the ABCD study.

A Distribution of PRS for ASD by SSRS categories. The non-ASD children were categorized into four groups according to the 33, 66, and 95 percentiles of their SSRS score (herein referred to as Q1, Q2, Q3, and the top 5%), where higher score indicated more prominent autistic-like traits. Children with ASD were classified as a distinct group. B The scatter plot between SSRS and PRS for ASD. A solid line indicates the fitting correlation between PRS and SSRS. SSRS was log-transformed to account for its right-skewed distribution. Group difference: ns p > 0.05, *p < 0.05, **p < 0.01. ASD autism spectrum disorder, SSRS short social responsiveness scale, ABCD adolescent brain cognitive development, PRS polygenic risk scores.

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