Table 3 Effect of NAD + /SIRT1 pathway PRS x ELS on the functional connectivity of NAc in sex-separated subpopulations.

From: Interaction of early life stress and NAD + /SIRT1 pathway genetic risk promotes depression

Linear regression results

Females

Beta

SE

P

R2

-0.3850

±0.1104

0.0010

0.1637

Males

 

0.3859

±0.1513

0.0145

0.1135

  1. Regression results of the association between the resting-state functional connectivity of the NAc (Z-scores) and the interaction of the NAD + /SIRT1 PRS and early life stress (ELS) values in a sex-specific manner. Beta–effect size, SE standard error, P–p-values of association, R2 – squared correlation coefficients.
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