Fig. 5: The de novo proteome is affected by low concentrations of Aβo and impact of eFT508 treatment. | Translational Psychiatry

Fig. 5: The de novo proteome is affected by low concentrations of Aβo and impact of eFT508 treatment.

From: Low concentrations of amyloid-beta oligomers induce synaptogenesis characteristic for mild cognitive impairment and alter the de novo proteome

Fig. 5: The de novo proteome is affected by low concentrations of Aβo and impact of eFT508 treatment.

(a) Volcano plot of all the proteins in the de novo proteome. The abscissas represent the fold change in log2, and the ordinates are p-values of t-tests between two groups in −log10 Red dots represent upregulated proteins, blue dots are downregulated proteins, and black dots illustrate unchanged proteins. Dot sizes are related to the fold change of each protein. (b) Venn diagram illustrating the total number of significantly altered de novo proteins under different treatment groups, highlighting both shared and unique changes.

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