Fig. 3: Load of protein truncating variants (PTVs) and synonymous variants in the dopamine response gene set in individuals who discontinued stimulants compared to individuals who continued.
From: Common and rare variant contributions to discontinuation of stimulant treatment in ADHD
Boxplot of odds ratios (OR) and 95% confidence intervals (CI) from logistic regression of the effect of protein truncating variants (PTVs) in the “dopamine response” gene set on stimulant discontinuation. ORs are shown as a solid vertical line and upper and lower 95%CI as the upper and lower boundaries of the boxes for DISCALL, DISCbelow16 and DISCabove16. Results are shown for PTVs in red, and for comparison the load of synonymous variants in green.
