Fig. 2: CAR-T cell expansion and persistence. | Blood Cancer Journal

Fig. 2: CAR-T cell expansion and persistence.

From: Donor-derived CARCIK-CD19 cells engineered with Sleeping Beauty transposon in acute lymphoblastic leukemia relapsed after allogeneic transplantation

Fig. 2

A CAR-T cells in peripheral blood by flow cytometry. B–C AUC-d28 (B) and Cmax-d28 (C) according to the severity of CRS. D AUC-d28 in patients who experienced CR or NR after CAR-T cell treatment. E AUC-d28 in patients with BM blasts post lymphodepletion less than or higher than 5%. F AUC-d28 in patients treated with CAR-T cells manufactured from identical sibling donors (ISD), haploidentical donors (Haplo), and matched unrelated donors (MUD). G Normal B-cell and CAR-T cell engraftment in the peripheral lood of patient 5 at different time points by flow cytometry. H B-cell recovery in CR and NR patients.

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