Table 4 Immune reconstitution data pre-vaccination in responders vs non-responders.

From: Humoral vaccine responses following Chimeric Antigen Receptor T-cell therapy for hematological malignancies

Immune variables

Overall

(n = 35)

Global responder

(n = 18)

Global non-responder

(n = 17)

P-value1

Absolute lymphocyte count (cells/mm3)

799 (114–3029)

793 (467–3029)

799 (114–3000)

0.92

Absolute CD-4 + T-cell count (cells/mm3)

246 (94–1000)

175 (98–673)

238 (43–1062)

0.84

Absolute CD-8 + T-cell count (cells/mm3)

196 (9–1848)

205 (71–1848)

158 (9–1522)

0.64

CD-19 + B-cell count (cells/mm3)

97 (0–780)

143 (37–780)

7 (0–477)

0.054

Immunoglobulin A (mg/dL)

31 (9–323)

49 (12–323)

9 (9–78)

0.041

Immunoglobulin G (mg/dL)

559 (109–985)

593 (220–985)

523 (109–892)

>0.99

Immunoglobulin M (mg/dL)

39 (16–78)

53 (8–174)

25 (5–234)

0.18

  1. 1Wilcoxon rank sum exact test with Bonferroni correction for multiple testing.