Table 4 Median time to major response, stratified by measurable M-protein by sPEP/uPEP at baseline (months).
n | Median time (months) | 95% CI | p-value | |
|---|---|---|---|---|
Only serum | ||||
dFLC | 440 | 1.15 | 1.06–1.24 | |
Serum M-protein | 440 | 1.48 | 1.34–1.62 | <0.001 |
Serum and urine | ||||
dFLC | 228 | 1.08 | 1.01–1.16 | |
Serum M-protein | 228 | 1.51 | 1.31–1.71 | <0.001 |
Urine M-protein | 228 | 3.19 | 2.57–3.80 | <0.001 |
Urine only | ||||
dFLC | 171 | 1.12 | 1.00–1.23 | |
Urine M-protein | 171 | 2.37 | 2.00–2.73 | <0.001 |