Table 3 Renal response in patients with baseline renal impairment.

From: Optimizing lenalidomide therapy in renal impairment: analysis of renal response in the prospective REMNANT study in transplant-eligible newly diagnosed multiple myeloma

Baseline eGFR (ml/min per 1.73m2)

Group B + C eGFR <50 (n = 81)

Group B eGFR 30–49 (n = 37)

Group C eGFR <30 (n = 44)

Renal response

62 (77%)

27 (73%)

35 (80%)

Complete responsea

46 (57%)

27 (73%)

19 (43%)

Partial responseb

5 (6%)

NA

5 (11%)

Minor responsec

11 (14%)

NA

11 (25%)

No response

17 (21%)

9 (24%)

8 (18%)

Not assessable

2 (2%)

1 (3%)

1 (2%)

  1. Data are n (%).
  2. eGFR estimated glomerular filtration rate in mL/min per 1.73m2, NA not applicable.
  3. aBaseline eGFR <50 mL/min per 1.73 m2—Best creatinine clearance Response >60 mL/min.
  4. bBaseline eGFR <15 mL/min per 1.73 m2—Best creatinine clearance Response 30–59 mL/min.
  5. cBaseline eGFR <15 mL/min per 1.73 m2—Best creatinine clearance Response 15–29 mL/min or baseline eGFR 15–29 mL/min per 1.73m2—Best creatinine clearance Response 30–59 mL/min.
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