Fig. 2: Transcriptomic profiling of FLT3ITD versus FLT3WT acute myeloid leukemia (AML). | Blood Cancer Journal

Fig. 2: Transcriptomic profiling of FLT3ITD versus FLT3WT acute myeloid leukemia (AML).

From: Prognostic impact of co-occurring FLT3 mutations across molecular subgroups in intensively treated acute myeloid leukemia: insights from real-world genomic data

Fig. 2

A Principal component analysis (PCA) demonstrating distinct clustering of transcriptomic profiles according to FLT3ITD mutation status. B Volcano plot depicting differentially expressed genes (DEGs) between FLT3ITD and FLT3WT AML samples. C Heatmap of normalized gene rexpression values of the top upregulated and downregulated DEGs. D Dot plot showing hallmark pathways significantly enriched in upregulated genes in FLT3ITD AML. E Dot plot showing hallmark pathways significantly enriched in downregulated genes in FLT3ITD AML.

Back to article page