Table 3 Multivariable cox regression analysis for myelodysplastic syndromes/neoplasms patients.
Variable | LFS | OS | ||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Agea | 1.031 (1.018–1.045) | <0.001 | 1.034 (1.019–1.049) | <0.001 |
Male | 1.039 (0.684–1.577) | 0.858 | 1.127 (0.732–1.736) | 0.588 |
Ferritin > 800 (ng/mL) | 1.576 (1.079–2.303) | 0.019 | 1.560 (1.056–2.304) | 0.025 |
LDH > 200 (ng/mL) | 1.680 (1.139–2.479) | 0.009 | 1.660 (1.109–2.485) | 0.014 |
AMC > 75 (ng/mL) | 1.037 (0.671–1.601) | 0.870 | 1.000 (0.641–1.559) | >0.999 |
ALC > 2200 (ng/mL) | 0.744 (0.466–1.188) | 0.215 | 0.818 (0.508–1.318) | 0.410 |
Presence of BM fibrosis | 1.421 (0.971–2.080) | 0.070 | 1.739 (1.172–2.580) | 0.006 |
Transfusion dependency | 1.113 (0.764–1.622) | 0.575 | 0.927 (0.629–1.368) | 0.704 |
Refined IPSS-M | <0.001 | <0.001 | ||
Very low/low/double negativeb | Reference | – | Reference | – |
Moderate low | 1.395 (0.569–3.417) | 0.467 | 1.385 (0.564–3.402) | 0.478 |
Moderate high | 3.042 (1.414–6.547) | 0.004 | 2.356 (1.065–5.210) | 0.034 |
High | 4.799 (2.242–10.272) | <0.001 | 3.860 (1.788–8.334) | 0.001 |
Very high | 11.821 (5.717–24.444) | <0.001 | 9.173 (4.426–19.008) | <0.001 |