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Autologous hematopoietic stem cell transplantation activity for lymphoma and multiple myeloma in China

Bone Marrow Transplantation volume 58, pages 349–352 (2023)Cite this article

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Autologous hematopoietic stem cell transplantation (AHSCT) is an important therapeutic strategy to improve the survival outcome of lymphoma and multiple myeloma (MM). The European Society for Blood and Marrow Transplantation reported that the number of AHSCT for MM increased sharply from 8032 to 37,743, the 5-year overall survival rate increased from 52 to 69% and the mortality decreased from 5.9 to 1.5% in 2015–-2019 compared with in 1995–1999 [1]. Limited data are available on the AHSCT performed in patients with lymphoma and MM stratified by age, sex and regions in the mainland of China. Therefore, we conducted the present study to provide epidemiological characteristics of AHSCT activity at national and provincial levels.

This retrospective study was organized by the autologous stem cell transplantation group of Chinese Society of Clinical Oncology which consisted of 211 AHSCT centers covering 29 provinces in mainland China. AHSCT centers were concentrated in the eastern region, including in Shandong (n = 22), Beijing (n = 19) and Guangdong (n = 18); few centers were located in the central and western regions including in Jilin (n = 2), Guizhou (n = 1) and Qinghai (n = 1). The AHSCT utilization rate was calculated by the number of AHSCT cases divided by the incident cases of the corresponding disease, and the incident data in national and provincial levels were extracted from the Global Burden of Disease Study 2019 using the standard source tool [2, 3].

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Data availability

All data generated or analysed during this study are included in this published article.

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Acknowledgements

We would like to thank all participating centers and their teams. This research was supported by the Clinical research fund for distinguished young scholars of Beijing Cancer Hospital (Grant No. QNJJ202106).

Author information

Author notes

  1. These authors contributed equally: Weiping Liu, Jie Ji, Dehui Zou, Yang Cao.

Authors and Affiliations

  1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute, 100142, Beijing, China

    Weiping Liu, Yuqin Song, Xiaopei Wang & Jun Zhu

  2. West China Hospital of Sichuan University, Department of Hematology, Chengdu, 610041, Sichuan, China

    Jie Ji

  3. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 300020, Tianjin, China

    Dehui Zou & Lugui Qiu

  4. Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Hematology, Wuhan, 430030, Hubei, China

    Yang Cao

  5. Xiangya Hospital, Central South University, National Clinical Research Center for Geriatric Diseases (Xiangya Hospital), Hunan Clinical Medical Research Center of Hematologic Neoplasms, Department of Hematology, Changsha, 410008, Hunan, China

    Yajing Xu

  6. The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Department of Hematology, Zhengzhou, 450008, Henan, China

    Jian Zhou

  7. The First Hospital of Jilin University, Department of Hematology, Changchun, 130021, Jilin, China

    Sujun Gao

  8. Peking University People’s Hospital, Peking University Institute of Hematology, 10044, Beijing, China

    Fengrong Wang

  9. Beijing Chaoyang Hospital, Capital Medical University, Department of Hematology, 100020, Beijing, China

    Wenming Chen

  10. Shanghai Changzheng Hospital, Naval Medical University, Department of Hematology, The Myeloma & Lymphoma Center, Shanghai, 200003, Shanghai, China

    Juan Du

  11. Hunan Cancer Hospital/The Affiliated Tumor Hospital of Xiangya Medical School, Central South University, Department of Lymphoma & Hematology, Changsha, 410013, Hunan, China

    Hui Zhou

  12. Zhongnan Hospital of Wuhan University, Department of Hematology, Wuhan, 430071, Hubei, China

    Fuling Zhou

  13. The First Affiliated Hospital, Zhejiang University School of Medicine, Bone Marrow Transplantation Center, Hangzhou, 310003, Zhejiang, China

    Jimin Shi

  14. Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Medical Center of Hematology, Chongqing, 400037, Chongqing, China

    Xi Zhang

  15. Changhai Hospital, Naval Medical University, Department of Hematology, Institute of Hematology, 200433, Shanghai, China

    Jianmin Yang

  16. Peking University Third Hospital, Department of Hematology, 100191, Beijing, China

    Hongmei Jing

  17. The First Afliated Hospital of Zhengzhou University, Department of Hematology, Zhengzhou, 450052, Henan, China

    Zhongxing Jiang

  18. Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Department of Hematology, 100730, Beijing, China

    Hui Liu

  19. National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Hematology department, Suzhou, 215000, Jiangsu, China

    Caixia Li

  20. Second Xiangya Hospital, Central South University, Department of Hemlatology, Changsha, 410011, Hunan, China

    Hongling Peng

  21. The First Affiliated Hospital of Wenzhou Medical University, Department of Hematology, Wenzhou, 325000, Zhejiang, China

    Songfu Jiang

  22. Nanfang Hospital, Department of Hematology, Southern Medical University, Guangzhou, 510515, Guangdong, China

    Xiaolei Wei

  23. The First Affiliated Hospital of Xi’an Jiaotong University, Department of Hematology, Xi’an, 710061, Shaanxi, China

    Pengcheng He

  24. Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Department of Hematology-Oncology, Chongqing, 400030, Chongqing, China

    Yao Liu

  25. The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Department of Lymphoma, Hangzhou, 310012, Zhejiang, China

    Haiyan Yang

  26. Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Hematology, Jinan, 250117, Shandong, China

    Zengjun Li

  27. Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Department of Hematology, Chengdu, 610071, Sichuan, China

    Xiaobing Huang

  28. The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, 400000, Chongqing, China

    Lin Liu

  29. Renji Hospital, Shanghai Jiao Tong University School of Medicine, Departments of Hematology, Shanghai, 200136, Shanghai, China

    Lijing Shen

  30. Qilu hospital of Shandong university, Department of Hematology, Jinan, 250012, Shandong, China

    Chuanfang Liu

  31. Harbin Institute of Hematology & Oncology, Department of Hematology & Oncology, Harbin, 150010, Heilongjiang, China

    Jun Ma

Authors
  1. Weiping Liu
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  2. Jie Ji
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  3. Dehui Zou
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  4. Yang Cao
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  5. Yajing Xu
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  9. Wenming Chen
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  10. Juan Du
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  11. Hui Zhou
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  12. Fuling Zhou
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  14. Xi Zhang
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  15. Jianmin Yang
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  16. Hongmei Jing
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  17. Zhongxing Jiang
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  18. Hui Liu
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  19. Caixia Li
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  20. Hongling Peng
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  21. Songfu Jiang
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  22. Xiaolei Wei
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  23. Pengcheng He
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  24. Yao Liu
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  35. Jun Zhu
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Contributions

LW conceived and designed the study, analyzed the data, and drafted and revised the paper. JJ, ZD and CY prepared and analyzed the data. QL and WX drafted and revised the manuscript. MJ and ZJ designed the study, interpreted the results, and drafted and revised the paper. All the authors have provided critical comments on the manuscript.

Corresponding authors

Correspondence to Jun Ma or Jun Zhu.

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The authors declare no competing interests.

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Cite this article

Liu, W., Ji, J., Zou, D. et al. Autologous hematopoietic stem cell transplantation activity for lymphoma and multiple myeloma in China. Bone Marrow Transplant 58, 349–352 (2023). https://doi.org/10.1038/s41409-022-01899-w

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  • DOI: https://doi.org/10.1038/s41409-022-01899-w

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